Vaccines & Immunogenicity World Congress 2023 Europe
London, United Kingdom
Day 1 - Monday 13th November 2023
- Novel vaccination approaches based on rational design of B and Tcell epitopes
- Progress on using recombinant DNA technology, advanced cellculture technique, immunoinformatics and rational design of immunogens for vaccine
development
VACCINE TECHNOLOGY AND PRODUCTION
- Impact of different inactivation and splitting procedures on vaccine composition, stability and recovery to support transfer of process technology
- Bioreactors for high cell density and continuous multi-stage cultivations as new options for process intensification in cell culture-based viral vaccine production
- High cell density and continuous multi-stage cultivations as options for process intensification in cell culture-based viral vaccine production
- Recent developments in establishing new designed cell lines, better host cell metabolism, advances in media design, and the use of mathematical models for process optimization
- Replication-deficient adenoviruses as potent vaccine development platforms for human candidate vaccines
- Cellular targets for improved manufacturing of virus-based biopharmaceuticals in animal cells
- Clarification of vaccines as critical step for product recovery and subsequent downstream purification
- Comprehensive view on different membrane based technologies and their application in vaccine clarification, challenges and best practice
REGULATORY COMPLIANCE AND CLINICAL TRIALS
- Continued evolution of safety evaluation processes that keep pace with advances in vaccine technology
- Regulatory aspects relevant to adjuvanted vaccines
- Summary of lessons learned from completed HIV/AIDS vaccine efficacy trials relevant to regulatory evaluation of clinical trial applications for vaccines in development
- Challenges regulators face when reviewing clinical trial applications
